Insights | Translation | Solutions
In February 2017 the Research Xchange Forum took place in Goettingen, Germany. This new platform was brought to live to learn about the latest insights from the fields of oncology and exchanging ideas as to their translation into viable solutions. Lectures given by 12 internationally renowned academics and leading biopharma R&D executives provided insights into the latest developments of their specific cancer research and therapy approaches.
The integration of single-use technology in fill and finish guarantees a high effective running machine while reducing the risk of cross-contamination and ensuring higher handling and production safety. Additionally, the overall efficiency is increasing due to skipping several cleaning and production steps.
Watch Dr. Germeroth‘s interview
Watch Dr. Germeroth‘s entire lecture
The development of a unique biologic platform to produce Immune mobilising monoclonal TCRs Against Cancer (ImmTAC) joins a growing armamentarium of immunotherapies that offer exciting approaches to deliver durable antibody responses in oncology.
Watch Nicola Smith‘s interview
Watch Prof. Dr. Maja Köhn's entire lecture
The novo findings from this trial highlight the multiplicity of mutation-based pathologies and pinpoint novel precision-based therapeutic strategies to pursue for intrahepatic cholangiocarcinoma, and potentially, in future basket trials of diverse tumors using a similar stratification approach.
Watch Prof. Dr. Andersen's interview
Watch Prof. Dr. Andersen's entire lecture
New discoveries in p53 research elucidate that the p53-Mdm2 system provides means to maintain DNA integrity and chromatin stability. These novel activities provide potential targets and opportunities for selectively interfering with tumor cell proliferation.
Watch Prof. Dr. med. Dobbelstein's interview
Watch Prof. Dr. med. Dobbelstein's entire lecture
Antibody drug conjugates (ADCs) seek to combine the cytotoxic potential of a pharmacologically active small-molecule drug with the specificity of mAbs. During this session, different types of ADC constructs, promising conjugation technologies, and also the challenges of ADCs are introduced.
Watch Zaki Sellam's interview
Watch Zaki Sellam's entire lecture
Facing the challenges in the development of suspension-based autologous cell therapies and manufacturing of personalized medicinal products using cell culture under GMP-conditions this study presents ways to overcome obstacles by employing the ambr 250 modular expansion system from Sartorius.
Watch Dr. Fraser's interview
Watch Dr. Fraser's entire lecture
Based on recent observations, state-of-the-art knowledge of ncRNAs’ functioning in cancer biology as well as their translational potential to serve as disease biomarkers in diagnostics and as novel therapeutic targets in cancer therapy are summarized and demonstrated by providing several examples.
Watch Prof. Dr. Slabý's interview
Watch Prof. Dr. Slabý's entire lecture
The research presented here focuses on USD studies of the bioprocessing of antibody products, the use of flocculation as a solution to processing challenges and the combined study of centrifugation and depth filtration as options in the primary recovery of a mammalian expression system.
Watch Dr. Alex Chatel's interview
Watch Dr. Alex Chatel's entire lecture
Sterility Testing of Drug Products – Challenges for Quality Departments
Dr. Susanne Roederstein,
Director Microbiology Marketing, Sartorius
On this event Sartorius and BD jointly focused with experts from the industry on Sterility Testing of Drug Products - Challenges for Quality Departments. International experts from the pharmaceutical and biotech industry and the National Regulatory & Safety Institutes covered topics of high interest around quality control, development, production and inspection.
Business Director Industry Western Europe
Key Account Manager Fluid Management
Laboratory Head and Head of QC Langenargen
Project Manager Single Use Equipment
Microbiological Expert EPD
Abbott Biologicals, Netherlands
Laboratory Head and Head of QC Microbiology Mooswiesen
Scientist for regulatory affairs | specialisation microbial safety
Paul Ehrlich Institute, Germany
Product Manager Microbiology
Vice President LPS Marketing
Senior Product Manager
Trends and Challenges in Quality Assurance and Regulatory Compliance
Dr. Gerhard Noelken, United Kingdom,
former Senior Director Technology & Innovations at Pfizer
Consultant for Infection Control and Hygiene
University of Goettingen, Germany
Senior Expert, Microbiology Sanofi Group
Managing Director, Institute of Technical Chemistry
University of Hanover, Germany
Head of Instrumental Analysis and Dissolution
Berlin-Chemie AG, Germany
Assessor for Microbiological Safety Regulations
Paul-Ehrlich Institute, Germany
Senior Director in the Technology & Innovation group
Global Manager Viral Clearance and Global Coordinator Virology
Charles River Biopharmaceutical Services GmbH, Germany
Quality Control, Head of Environmental Monitoring
CSL Behring, Germany
Minerva Biolabs GmbH, Germany
Senior Scientist, RND – Endotoxin